
Best Low-Calorie High-Protein Powder

If you're looking for the best high-protein, low-calorie powder, you probably want to build muscle, lose weight, or maintain a healthy diet. But with so many options available, choosing the right protein powder can be overwhelming.
In this article, I’ll break down the top 5 protein powders that offer the highest protein content with the lowest calories, helping you maximize your fitness goals without extra sugar or unnecessary fillers.
What Makes a Great High-Protein, Low-Calorie Powder?
Not all protein powders are created equal. The best options share these key characteristics:
✔️ High Protein-to-Calorie Ratio – At least 20-25g of protein per serving with under 150 calories.
✔️ Minimal Sugar & Carbs – Avoid unnecessary fillers that add calories without benefits.
✔️ Clean Ingredients – No artificial additives or hidden sugars.
✔️ Easy Mixability & Good Taste – Because no one likes a clumpy shake.
✔️ Digestibility – Especially if you have a sensitive stomach (lactose-free and plant-based options available).
Now, let's get into the best low-calorie protein powders of 2025!
Top 5 Best Low-Calorie High-Protein Powders in 2025
1. Optimum Nutrition Gold Standard Whey – Best Overall
🥤 Protein per serving: 24g
🔥 Calories per serving: 120
💰 Price per serving: $1.10
Why It’s the Best:
✔️ High-quality whey protein isolate blend.
✔️ Low in sugar and fat.
✔️ Fast absorption, perfect for post-workout recovery.
Cons:
❌ Contains artificial sweeteners.
💡 Best for: Anyone looking for an affordable, high-quality whey protein with great mixability and taste.
2. Dymatize ISO100 – Best for Weight Loss
🥤 Protein per serving: 25g
🔥 Calories per serving: 110
💰 Price per serving: $1.40
Why It’s Great for Weight Loss:
✔️ Zero sugar and almost no fat.
✔️ Made from 100% whey protein isolate, making it easier to digest.
✔️ Low calorie, high protein formula helps preserve lean muscle.
Cons:
❌ More expensive than standard whey.
💡 Best for: People on a low-calorie diet who need a pure, fast-digesting protein.
3. Orgain Organic Protein – Best Plant-Based Option
🥤 Protein per serving: 21g
🔥 Calories per serving: 150
💰 Price per serving: $1.30
Why It’s the Best Vegan Protein Powder:
✔️ Made from pea, brown rice, and chia seed protein.
✔️ No dairy, gluten, soy, or artificial ingredients.
✔️ Great for digestion and easy on the stomach.
Cons:
❌ Higher in carbs compared to whey-based proteins.
💡 Best for: Vegans and people with lactose intolerance who need a clean, plant-based protein source.
4. MyProtein Impact Whey – Best Budget Option
🥤 Protein per serving: 21g
🔥 Calories per serving: 103
💰 Price per serving: $0.85
Why It’s Affordable & Effective:
✔️ One of the cheapest high-quality whey proteins available.
✔️ Low calorie and high protein for cutting weight.
✔️ Simple ingredients with no unnecessary additives.
Cons:
❌ Taste is not as strong as premium brands.
💡 Best for: Budget-conscious buyers who want a simple, effective protein powder.
5. Transparent Labs 100% Grass-Fed Whey – Best Clean Ingredient Option
🥤 Protein per serving: 28g
🔥 Calories per serving: 120
💰 Price per serving: $1.60
Why It’s the Cleanest Protein Powder:
✔️ Made from grass-fed whey protein isolate.
✔️ No artificial sweeteners, colors, or fillers.
✔️ Highest protein content per calorie.
Cons:
❌ More expensive than regular whey.
💡 Best for: People who want all-natural ingredients with maximum protein content.
Comparing the Best High-Protein Low-Calorie Powders
Product | Protein (g) | Calories | Type | Best For |
---|---|---|---|---|
Optimum Nutrition Gold Standard Whey | 24g | 120 | Whey Blend | Best Overall |
Dymatize ISO100 | 25g | 110 | Whey Isolate | Weight Loss |
Orgain Organic Protein | 21g | 150 | Plant-Based | Vegan Diet |
MyProtein Impact Whey | 21g | 103 | Whey Concentrate | Budget Option |
Transparent Labs 100% Grass-Fed Whey | 28g | 120 | Whey Isolate | Clean Ingredients |
Why Protein Powders Are Great for Weight Loss and Muscle Growth
Protein is essential for building muscle, losing fat, and staying full longer. Here’s why:
✔️ Boosts metabolism – High-protein diets increase calorie burning.
✔️ Supports muscle growth – Prevents muscle loss when cutting weight.
✔️ Keeps you full longer – Reduces cravings and unnecessary snacking.
✔️ Fast & convenient – An easy way to get high-quality protein anytime.
💡 Pro Tip: If you’re on a weight loss journey, choose a protein powder under 150 calories per serving and pair it with a healthy diet.
User Reviews: What People Say About These Protein Powders
We checked real customer reviews on Amazon to see what buyers think:
⭐ Optimum Nutrition Gold Standard Whey – "Mixes easily and tastes great. Perfect for post-workout recovery!"
⭐ Dymatize ISO100 – "Best for weight loss. No bloating, no sugar, and super high protein content."
⭐ Orgain Organic Protein – "Love that it’s plant-based and doesn’t upset my stomach!"
⭐ MyProtein Impact Whey – "Great value for the price. Simple and effective."
⭐ Transparent Labs Grass-Fed Whey – "Cleanest protein powder I’ve ever tried. No junk ingredients."
Conclusion
The best low-calorie high-protein powders provide quality protein, great taste, and clean ingredients. Whether your goal is muscle growth, fat loss, or meal replacement, there’s a perfect protein powder for you.